Turn a bad situation into a good one.
Historically, the people in this world who achieved the most success were also those who overcame great obstacles. Your infirmities actually help you greatly—Beethoven probably composed such beautiful music because he was deaf, Helen Keller probably embarked on a brilliant career due to her blindness and deafness, and Leo Tolstoy probably wrote such an immortal novel because of all the torture he went through in his life. The most beautiful things are born out of pain, by those who care enough to try.
Always trying to better a bad situation will lead you to success. Giving up will not.